Article Correctness Is Author's Responsibility: How ketamine combats depression June 1, 2020 Author: Neuroscience News Category: antidepressantsThe article below may contain offensive and/or incorrect content. Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine.