An experimental small molecule helped restore the removal of mitochondria from dopamine-producing neurons in the brain. The findings may help in the development of new therapies for Parkinson’s disease.
Article Correctness Is Author's Responsibility: 15 Novel Biomarkers for Diseases Predisposing to Dementia Identified
15 protein biomarkers have been identified as being linked to late-onset dementias. The biomarkers can predict cognitive decline and risk for dementia up to 20 years before the onset of symptoms.
Article Correctness Is Author's Responsibility: Machine Learning Approach for Predicting Risk of Schizophrenia Using a Blood Test
Blood tests revealed specific epigenetic biomarkers for schizophrenia. Researchers applied machine learning to analyze the CoRSIVs region of the human genome to identify the schizophrenia biomarkers. Testing the model with an independent data set revea…
Article Correctness Is Author's Responsibility: Exercise Improves Health Through Changes to DNA
Exercise rewires the enhancers in DNA regions associated with the risk of disease development.
Article Correctness Is Author's Responsibility: Molecular Insights Into Primate Hippocampal Aging
Study establishes a comprehensive single-nucleus transcriptomic atlas of the aging primate hippocampus and provides key information about age-related molecular signatures at the single-cell level.
Article Correctness Is Author's Responsibility: Does Testosterone Influence Success? Not Much
Study reveals there is little evidence to suggest high testosterone meaningfully affects socioeconomic status, health, or risk-taking in men or women.
Article Correctness Is Author's Responsibility: Discovery Points to Ketamine’s Long-Term Antidepressant Effects
The MeCP2 gene influences ketamine’s behavioral effect and strengthens synapses, leading to an improvement in the drug’s antidepressant effect over time.
Article Correctness Is Author's Responsibility: Fruit Compound May Have Potential to Prevent and Treat Parkinson’s Disease
Farnesol, a naturally occurring compound found in berries and other fruits, prevents the loss of dopamine-producing neurons and reverses Parkinson’s associated damage to the brain in mouse models.
Article Correctness Is Author's Responsibility: Biomarker Could Help Diagnosis Schizophrenia at an Early Age
Study reveals an abundance of the CRMP2 protein in people with schizophrenia. The findings could lead to a blood-based biomarker test for the mental health disorder.
Article Correctness Is Author's Responsibility: Early Signs of Frontotemporal Dementia Found in Personalized Cerebral Organoids
Researchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn’s disease may help prevent neuron death associated with FTD.
Article Correctness Is Author's Responsibility: Rare Inherited Variants in Previously Unsuspected Genes May Confer Significant Risk for Autism
Study identifies a rare class of genetic differences transmitted from non-autistic parents to their children on the autism spectrum.
Article Correctness Is Author's Responsibility: Administering Opioids to Pregnant Mice Alters Behavior and Gene Expression in Offspring
Alterations in long-term social behavior and gene expression were observed in the offspring of mice exposed to pain-killing opioids during pregnancy.
Article Correctness Is Author's Responsibility: A Direct Genetic Link to ASD Identified
Researchers identified a novel, direct link between autism and the SUV39H2 gene.
Article Correctness Is Author's Responsibility: Autophagy May Be the Key to Finding Treatments for Early Huntington’s Disease
Disruption of autophagy may be at the root of the cognitive deficits experienced by those with Huntington’s disease.
Article Correctness Is Author's Responsibility: Impairments Found In Neurons Derived From People With Schizophrenia and Genetic Mutation
The release of neurotransmitters in the brain is impaired in people with schizophrenia who have the neurexin 1 gene mutation.
Article Correctness Is Author's Responsibility: Mini-Brain Study Shows How Environmental Risk Factors Can Amplify Genetic Risks for Autism
Using human stem cells to develop a brain organoid model, researchers were able to show exposure to a common pesticide synergizes with an autism-linked gene mutation. The study provides clear evidence that genetics and environment may combine to disrup…
Article Correctness Is Author's Responsibility: Antibiotics in Early Life Could Affect Brain Development
Early-life exposure to antibiotics could impact brain development in areas associated with emotional and cognitive function, a new study reports. Researchers found penicillin exposure in infant mice altered the microbiome and gene expression in key are…
Article Correctness Is Author's Responsibility: A Variety of Factors Beyond Age Influence Reaction Time
A new study reveals a number of different factors, including smoking, age, education levels, sex, handedness, and family medical history, which can have an impact on reaction time.
Article Correctness Is Author's Responsibility: Long-Term Memory Setup Requires a Reliable Delivery Crew
Research shows the role the molecular hauler KIF5C plays in long-term memory and synaptic plasticity.
Article Correctness Is Author's Responsibility: Recent Study Identifies 11 Candidate Genetic Variants for Alzheimer’s Disease
Study reveals eleven genetic variants spanning ten genes, including previously unknown variants in two known Alzheimer’s risk genes.
